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RCC1 (regulator of chromosome condensation 1 ) Blocking Peptide (the C terminal of RCC1)(100ug)

RCC1 (regulator of chromosome condensation 1 ) Blocking Peptide (the C terminal of RCC1)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-RCC1 Antibody (ARP61300_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP61300
Size: 100ug
Weight: 45kDa
Gene: The peptide is characterized by mass spectroscopy
Format: Lyophilized powder
Target: RCC1 is a Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.
Alternative names: CHC1; RCC1-I
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