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RBM35B Antibody (OAPB01253)

RBM35B Antibody (OAPB01253)

RBM35A, also known as ESRP2, is a mRNA splicing factor that with its related protein RBM35A (ESRP1) are coordinators of an epithelial cell-type-specific splicing program. Both RBM35B and RBM35A are involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs, suggesting that these proteins are global regulators of an epithelial regulatory network. Loss of this global ESRP-regulated epithelial splicing programme induces the phenotypic changes in cell morphology that are observed during the epithelial-mesenchymal transition.

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SPECIFICATIONS

Size

0.1 mg

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum, Mouse

Presku

OAPB01253

Target

Epithelial splicing regulatory protein 2

Alternative Names

RNA-binding motif protein 35B; RMB35B; Epithelial splicing regulatory protein 2; ESRP2

SUPPLIER INFO

Aviva Systems Biology Incorporated

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