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RBBP8 (retinoblastoma binding protein 8) Blocking Peptide (the middle region of RBBP8)(100ug)

RBBP8 (retinoblastoma binding protein 8) Blocking Peptide (the middle region of RBBP8)(100ug)


Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-RBBP8 Antibody(ARP50888_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP50888
Size: 100ug
Weight: 98kDa
Gene: 5932
Format: Lyophilized powder
Target: RBBP8 is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.
Alternative names: CTIP; RIM