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RBBP6 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 251916

RBBP6 Antibody

E3 ubiquitin-protein ligase RBBP6 (RBBP6) is an E3 ubiquitin-protein ligase which promotes ubiquitination of YB, Xenopus/Amphibian,1, leading to its degradation by the proteasome. RBBP6 plays a role as a scaffold protein to promote the assembly of the p53/TP53-MDM2 comple, Xenopus/Amphibian,, resulting in the increase of MDM2-mediated ubiquitination and degradation of p53/TP53. RBBP6 functions as negative regulator of p53/TP53, leading to both apoptosis and cell growth.

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SPECIFICATIONS

Catalog Number

251916

Size

0.1 mg

Applications

WB

Reactivities

Hum

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human RBBP6.

Isotype

Rabbit Ig

Accession

Q7Z6E9

Additional Info

Retinoblastoma-binding protein 6; p53-associated cellular protein of testis; Proliferation potential-related protein; Protein P2P-R; Retinoblastoma-binding Q protein 1; RBQ-1; RBBP6; P2PR; PACT; RBQ1

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