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RB1 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 252178

RB1 Antibody

Retinoblastoma-associated protein (RB1) is a key regulator of entry into cell division that acts as a tumor suppressor. RB1 acts as a transcription repressor of E2F1 target genes. The underphosphorylated, active form of RB1 interacts with E2F1 and represses its transcription activity, leading to cell cycle arrest. Defects in RB1 are the cause of childhood cancer retinoblastoma (RB). RB is a congenital malignant tumor that arises from the nuclear layers of the retina. RB1 is e, Xenopus/Amphibian,pressed in the retina.

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SPECIFICATIONS

Catalog Number

252178

Size

0.1 mg

Applications

IHC

Reactivities

Hum

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.5% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human RB1.

Isotype

Rabbit Ig

Accession

P06400

Additional Info

RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110

SUPPLIER INFO

ABBIOTEC

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