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Rat Anti- Mouse CD3e- PE(0.2 mg)

Rat Anti- Mouse CD3e- PE(0.2 mg)

CD3epsilon, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chain ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). It is expressed on all T cells of all mouse strains.1, 2 CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. The monoclonal antibody C363.29B recognizes an epitope on the 25kD epsilon chain of the CD3/TCR complex.1 In the presence of Fc receptor-bearing accessory cells, soluble C363.29B can activate primed and naпїЅve T cell in vitro. Immobilized C363.29 monoclonal antibody can also activate both normal T lymphocytes and cloned T cell lines provided the appropriate accessory signals are present.1, 3, 4 The monoclonal antibody is cytolytic, easily used for cell surface staining and a good immunoprecipitating antibody.1

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SPECIFICATIONS

Size

0.2 mg

Applications

FC

Hosts

Rat

Clone

C363.29B

Format

R- phycoerythrin (R- PE) Conjugate

Presku

OASB00257

Isotype

IgG2b

SUPPLIER INFO

Aviva Systems Biology Incorporated

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