logo
logo
Rat Anti- Mouse CD25/IL- 2Ra- SPRD(0.1 mg)

Rat Anti- Mouse CD25/IL- 2Ra- SPRD(0.1 mg)

The IL-2 receptor (IL-2R) exists in three alternative forms made up from the individual components of CD25, CD122, and CD132. CD25 represents the low affinity alpha chain of the IL-2R, a type I transmembrane glycoprotein containing two CCP domains. It is rich in O-linked carbohydrates and has a short cytoplasmic tail.14 CD25 is expressed on activated T cells, B cells, NK cells and monocytes of all mouse strains tested.2, 3, 15 Expression of CD25 on activated T lymphocytes is transitory and endogenously regulated.4 CD25 is expressed on precursor B cells in bone marrow. Its expression is initiated by functional rearrangement and expression of IgM heavy chain genes and is down-regulated when immature B cells mature and express IgD.5 It is expressed at a higher level on CD4+CD8+ thymocytes.5, 6 It is also expressed on cultured epidermal Langerhans cells.7 The biochemical features of murine CD25 have been characterized in detail.8-10 The 3C7 monoclonal antibody reacts with an epitope of CD25 which is distinct from that recognized by clone 7D4.2, 11, 12 3C7, used in combination with 7D4 in culture, results in higher levels of inhibition of proliferation d

Prices direct from Aviva Systems Biology Incorporated

Quick response times

Exclusive Absave savings/discounts

SPECIFICATIONS

Size

0.1 mg

Hosts

Rat

Clone

3C7

Format

SpectralRed (SPRD) Conjugate

Presku

OASB00400

Isotype

IgG2b

Latest promotions

New brilliant antibodies, and new lower prices!For flow cytometry reagents in general, \"bright is better.\" The violet-excitable BD Horizon™ BV421 and...

Buy any polyclonal or monoclonal antibody from our extensive range of pre-made antibodies and for a limited time only receive a $50 discount!(T&C apply:...

Did your supplier increase the price of Fetal Bovine Serum? Did they substitute the US Origin with USDA? Well say no more! Innovative Research is still...

10% Discount on 2 Rabbit Polyclonal Antibody Service. With over 20 years experience, SDIX has developed into the premier US custom antibody producer,...

For the past decade scientists have extensively used ATS secondary toxin conjugates to make their own targeted toxins for in vitro use.The ability to combine...

We're so sure that you'll prefer Cayman Assay kits over your present brand that we're willing to give you a free assay kit to prove it!

Bulk Cytokines with Custom Vialing.20 - 50% off cytokines, growth factors, chemokines and more...For a limited time Cell Sciences is offering substantial...

Are you planning to have a customised antibody made for your research?Since 2000, Everest has been producing a catalog containing thousands of affinity...