Rat Anti- Mouse CD24/HSA- APC(0.1 mg)

CD24, also known as heat stable antigen, is a phosphatidylinositol-linked cell surface glycoprotein that is expressed at all stages of B cell development and on most thymocytes.^1-3 The absence of expression from mature T cells is closely associated with their maturation from CD4⁺CD8⁺CD24⁺ thymocytes to either CD4⁺CD8^-CD24^- or CD4^-CD8⁺CD24^- T cells. CD24 is also present on mouse granulocytes, monocytes, Langerhans cells and erythrocytes.^4-6 Its ligand is P-selectin (CD62P).⁷ CD24 may play a role in regulation of B cell proliferation and differentiation, and it has been proposed that heat stable antigen promotes homotypic adhesion between B lymphocytes.^1-3 The monoclonal antibody 91 can be used to inhibit B-cell differentiation.⁸