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Rat Anti- Mouse CD11a/LFA- 1a- PE/CY7(0.1 mg)

Rat Anti- Mouse CD11a/LFA- 1a- PE/CY7(0.1 mg)

The monoclonal antibody I21/7 reacts with the alpha subunit of mouse CD11a, also known as Leukocyte Function-associated Antigen-1 (LFA-1) and a member of the integrin family of cell adhesion molecules.1, 2 The antigen is expressed on thymocytes, T and B lymphocytes, and on non-lymphoid cells in the bone marrow.2 CD11a appears to be an essential component for T-cell activation by antigen-presenting cells and is important for cell-mediated killing. Co-stimulatory signaling by LFA-1 is achieved by pairing with its ligand, CD54/ICAM-1.1, 2

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SPECIFICATIONS

Size

0.1 mg

Applications

FC

Hosts

Rat

Clone

I21/7

Format

R- phycoerythrin- Cyanine 7 (R- PE- CY 7) Conjugate

Presku

OASB00309

Isotype

IgG2a

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