Rat Anti- Mouse BP- 1/Ly- 51- FITC(0.5 mg)

BP-1, also known as Ly-51/6C3 antigen, is a type II homodimeric transmembrane glycoprotein formed by two disulfide-linked chains of 140 kDa.^{1, 2} Originally identified on the surface of pre-B cell lymphomas^{1, 3} the cDNA encoding BP-1/Ly-51/6C3 has been cloned and found to represent aminopeptidase A.^{4, 5} It is expressed at high levels on bone marrow stromal cell lines which support in vitro B lymphopoiesis and on a wide variety of mouse tissues known to possess aminopeptidase activity.^6-8 Subsets of normal bone marrow pre-B and B cells express low levels of BP-1/Ly-51/6C3, which is rapidly upregulated on pre-B cells in the presence of IL- 7.^{9, 10} The BP-1/Ly-51/6C3 marker is commonly used to identify B cells in different stages of development.¹¹