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Rassf5 Antibody - C-terminal region (ARP59675_P050)

Rassf5 Antibody - C-terminal region (ARP59675_P050)

This is a rabbit polyclonal antibody against Rassf5. It was validated on Western Blot by Aviva Systems Biology. At Aviva Systems Biology we manufacture rabbit polyclonal antibodies on a large scale (200-1000 products/month) of high throughput manner. Our antibodies are peptide based and protein family oriented. We usually provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (info@avivasysbio.com).

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SPECIFICATIONS

Size

50ug

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse

Format

Lyophilized powder

Presku

ARP59675_P050

Target

Rassf5 is a potental tumor suppressor. It seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. It may be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS1 and KRAS induced apoptosis.

Weight

47kDa

Gene Id

54354

Alternative Names

1300019G20Rik; AU042887; Maxp1; Nore1; Nore1A; Nore1B; Rapl

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