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RASSF1 (Ras association (RalGDS/AF-6) domain family member 1) Blocking Peptide (the C terminal of RASSF1)(100ug)

RASSF1 (Ras association (RalGDS/AF-6) domain family member 1) Blocking Peptide (the C terminal of RASSF1)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-RASSF1 Antibody(ARP59681_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP59681
Size: 100ug
Weight: 30kDa
Gene: 11186
Format: Lyophilized powder
Target: This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Alternative names: 123F2; NORE2A; RASSF1A; RDA32; REH3P21
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