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RASSF1 Antibody

RASSF1 Antibody

Cat no: 251602


Supplier: ABBIOTEC
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RASSF (Ras association domain family 1A) protein is a potential tumor suppressor. Required for death receptor-dependent apoptosis. Mediates activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation. When associated with MOAP1,Porcineromotes BA, Xenopus/Amphibian, conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation. Isoform A interacts with CDC20, an activator of the anaphase-promoting comple, Xenopus/Amphibian,, APC, resulting in the inhibition of APC activity and mitotic progression. Inhibits proliferation by negatively regulating cell cycle progression at the level of G1/S-phase transition by regulating accumulation of cyclin D1 protein.
Catalogue number: 251602
Reactivities: Human, Mouse, Rabbit
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: Q9NS23
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human RASSF1A.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: RASSF1; Ras association domain family 1A; Ras association domain-containing protein 1; RDA32