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RASGRP1 (RAS guanyl releasing protein 1 (calcium and DAG-regulated) ) Blocking Peptide (the C terminal of RASGRP1)(100ug)

RASGRP1 (RAS guanyl releasing protein 1 (calcium and DAG-regulated) ) Blocking Peptide (the C terminal of RASGRP1)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-RASGRP1 Antibody (ARP63788_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP63788
Size: 100ug
Weight: 90kDa
Gene: 10125
Format: Lyophilized powder
Target: This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE).
Alternative names: CALDAG-GEFI; CALDAG-GEFII; MGC129998; MGC129999; RASGRP; V; hRasGRP1
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