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RASGRF1 (Ras protein-specific guanine nucleotide-releasing factor 1) Blocking Peptide (the middle region of RASGRF1)(100ug)

RASGRF1 (Ras protein-specific guanine nucleotide-releasing factor 1) Blocking Peptide (the middle region of RASGRF1)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-RASGRF1 Antibody(ARP56515_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP56515
Size: 100ug
Weight: 145kDa
Gene: 5923
Format: Lyophilized powder
Target: The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alternative names: CDC25; CDC25L; GNRP; GRF1; GRF55; H-GRF55; PP13187
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