Supplier:
Aviva Systems Biology IncorporatedRASGRF1 (Ras protein-specific guanine nucleotide-releasing factor 1) Blocking Peptide (the middle region of RASGRF1)(100ug)
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SPECIFICATIONS
Size
100ug
Reactivities
Hum
Format
Lyophilized powder
Presku
AAP56515
Target
The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Weight
145kDa
Gene Id
5923
Alternative Names
CDC25; CDC25L; GNRP; GRF1; GRF55; H-GRF55; PP13187
SUPPLIER INFO
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