GTP-binding nuclear protein Ran (RAN) is a GTP-binding protein involved in nucleocytoplasmic transport. RAN is required for the import of protein into the nucleus and also for RNA e, Xenopus/Amphibian,port. RAN is involved in chromatin condensation and control of cell cycle. The comple, Xenopus/Amphibian, with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TP, Xenopus/Amphibian,2 to microtubules. RAN enhances AR-mediated transactivation, which decreases as the poly-Gln length within AR increases.