Supplier:
Aviva Systems Biology IncorporatedRag1 (recombination activating gene 1) Blocking Peptide (the C terminal of Rag1)(100ug)
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SPECIFICATIONS
Size
100ug
Reactivities
Mouse
Format
Lyophilized powder
Presku
AAP42949
Target
As a catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities.
Weight
119kDa
Gene Id
19373
Alternative Names
Rag-1
SUPPLIER INFO
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