Reactivities: | Human |
Presku: | AAP57717 |
Size: | 100ug |
Weight: | 32kDa |
Gene: | 5810 |
Format: | Lyophilized powder |
Target: | This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described. |
Alternative names: | HRAD1; REC1 |