Rab25 (3F12) Antibody

Rab25 is a 28 kDa protein, belongs to the small GTP-ase superfamily. Members of the Ras-related superfamily of GTP binding proteins which includes Ras, Rho, Rab and ARF subfamilies, e, Xenopus/Amphibian,hibit 30-50% similarity with Ras p21. Rab proteins play an important role for either in endocytosis or in biosynthetic protein transport. The possibility that Rab proteins might also direct the e, Xenopus/Amphibian,ocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, the SEC4 protein, which is 40% similar to Rab proteins, is associated with secretory vesicles. Rab proteins located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactios.