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PYK2 (5E2D) Antibody

PYK2 (5E2D) Antibody

Cat no: 252776


Supplier: ABBIOTEC
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PYK2 (PTK2B protein tyrosine kinase 2 beta) is a cytoplasmic protein tyrosine kinase. It is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. PYK2 may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flu, Xenopus/Amphibian, and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation,Mouse,embrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK and the SH2 domain of GRB2. This protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies.
Catalogue number: 252776
Reactivities: Human
Applications: Western Blot
Size: 0.1 ml
Accession: Q14289
Antigen: Purified recombinant fragment of PYK2(aa815-997) e, Xenopus/Amphibian,pressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type: Mouse Monoclonal Antibody
Isotype: Mouse IgG2a
Clonality: 5E2D5
Additional info: Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Proline-rich tyrosine kinase 2; Related adhesion focal tyrosine kinase RAFTK; FAK2; PYK2; RAFTK ;PTK2B;