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PYHIN1 (pyrin and HIN domain family, member 1) Blocking Peptide (100ug)

PYHIN1 (pyrin and HIN domain family, member 1) Blocking Peptide (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-PYHIN1 antibody (Catalogue #: ARP50876_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP50876
Size: 100 ug
Weight: 51kDa
Gene: 149628
Format: Lyophilized powder
Target: PYHIN1 belongs to the HIN-200 family. This protein is major mediator of the tumor suppressor activity of IFN in breast cancer cells. It promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization, and HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells.
Alternative names: IFIX; MGC23885; RP11-520H16.1
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