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PYGB (Human) cDNA (1ug)

PYGB (Human) cDNA (1ug)

Supplier: Aviva Systems Biology Incorporated
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The ORF of human PYGB is amplified by PCR using a high fidelity enzyme and sub-cloned into a Prokaryotic expression vector under the control of the tac promoter. The expression of the gene has been confirmed by Western blot using an anti-PYGB polyclonal antibody.
Presku: ANA11235
Size: 1ug
Gene: 5834
Target: The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation.
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