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Purified anti-XBP-1s

Purified anti-XBP-1s

Cat no: 647502

Supplier: BioLegend
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XBP-1 is a transcription factor containing a bZIP domain. It was first identified because of its binding ability to X-box, a conserved transcriptional element in the promoter of human HLA DR gene. XBP-1 has multiple functions. It controls MHC class II gene regulation and is also essential for differentiation of plasma cells. XBP-1 upregulates as part of the ER stress response, also known as the unfolded protein response. Unspliced XBP-1 is 261 amino acids and migrates on the SDS-PAGE around 33 kD; spliced XBP-1, recognized by clone 143F, is371 amino acids and migrates around 55 kD. 
Catalogue number: 647502
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 100 microg
Clone: 143F
Gene: 7494
Dilutions: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1 to 2 microg per ml. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C.
Concentration: 0.5 mg/ml
Antigen: XBP-1s recombination protein
Isotype: Mouse IgG2a
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: X-box binding protein 1
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