Purified anti-TIF1beta (KAP-1, TRIM28) Phospho (Ser473)

Transcriptional intermediary factors (TIFs) are a group of transcriptional coactivators and corepressors that regulate gene expression by modulating chromatin structure and assembly of transcription initiation complexes. TIF1beta is a member of the TIF1 subfamily of chromatin-associated TIFs that play a key role in many developmental and physiological processes. Studies using knockout mice reveal the important function of TIF1beta in regulating genomic imprinting, T cell activation, and T cell tolerance.

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SPECIFICATIONS

Catalog Number

654101

Size

25 microg

Applications

WB

Hosts

Mouse

Reactivities

Hum

Clone

11G10SC

Antigen

Modified peptide: VKRSRpSGEGEVC.

Gene Id

21849

Isotype

Mouse IgG1, kappa

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 1.0 microg per ml. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

0.5 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

Upon receipt, store undiluted at 4C.

Alternative Names

TRIM28 pS483, KAP-1 pS473, KRIP-1 pS473

Regulatory Status

RUO