Purified anti-Syk

Syk is a cytoplasmic 72 kD non-receptor tyrosine kinase that is widely expressed in hematopoietic cells. The Syk kinase associates with a number of proteins including c-Src, Lck, Lyn, Fyn, Vav1, STAT3, SHP1, Grb2, and LAT to couple immunoreceptors to downstream signaling events mediating cellular proliferation, differentiation, and phagocytosis. Syk is modified by phosphorylation on multiple tyrosine sites

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SPECIFICATIONS

Catalog Number

644302

Size

100 microg

Applications

FC, ICC, IP, WB

Hosts

Mouse

Reactivities

Hum

Clone

4D10.2

Antigen

Human Syk peptide aa314-339

Gene Id

6850

Isotype

Mouse IgG2a, kappa

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 0.5-1 microg per ml antibody dilution buffer. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

0.5 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C.

Alternative Names

Spleen tyrosine kinase, protein tyrosine kinase SYK

Regulatory Status

RUO