Purified anti-SWAP70

SWAP70 was initially isolated as a component of an isotype switch recombination complex (SWAP) from activated B lymphocytes. It translocates from cytoplasm to the nucleus upon B cell activation. SWAP70 interacts with F-actin and RAC, binds to PI(3,4)P2, and regulates membrane ruffling and lamellipodia formation in response to growth factor stimulation.

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SPECIFICATIONS

Catalog Number

654702

Size

100 microg

Applications

WB

Hosts

Mouse

Reactivities

Hum

Clone

9D9A19

Antigen

Partial human SWAP70 recombinant protein (89-585 aa).

Gene Id

23075

Isotype

Mouse IgG1, kappa

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.1-0.5 microg per ml. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

0.5 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

Upon receipt, store undiluted at 4C.

Alternative Names

SWAP switching B-cell complex 70 kD subunit, switch-associated protein 70

Regulatory Status

RUO