Purified anti-SOX2

This rabbit polyclonal antibody recognizes human SOX2, also known as SRY (sex determining region Y)-box 2 and ANOP3. SOX2 is a nuclear protein with a predicted molecular weight of 34 kD. SOX2 belongs to the SOX (SRY-box containing gene) gene family which encodes a group of transcription factors defined by the conserved high motility group (HMG) DNA-binding domain. They are involved in the regulation of embryonic development and in the determination of cell fate. Defects in SOX2 are a cause of true or primary anophthalmos, also called anophthalmia or ANOP3. Anophthalmos is a developmental defect characterized by complete absence of the eyes (rare) or by the presence of vestigial eyes.

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SPECIFICATIONS

Catalog Number

651901

Size

50 microl

Applications

WB

Hosts

Rabbit

Reactivities

Hum

Clone

Poly6519

Antigen

Full length recombinant SOX2 protein

Gene Id

6657

Isotype

Rabbit Polyclonal

Clonality

Polyclonal

Dilutions

Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 microl per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

-20 C

Concentration

Shipping Temp

Ambient RT

Storage Buffer

Upon receipt, store undiluted at -20C.

Alternative Names

SRY (sex determining region Y)-box 2, ANOP3, SOX-2

Regulatory Status

RUO