Purified anti-SIK2

SIK2 (Salt inducible kinase 2) belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, and AMP-activated protein kinase (AMPK) subfamily, predicted molecular weight 104 kD. SIK2 is found in adipocytes and might be involved in metabolic regulation in adipose tissue. Sik2 phosphorylates ser794 of human insulin receptor substrate-1 (IRS1) in insulin-stimulated adipocytes, playing important roles in modulating the insulin-signaling cascade of adipocytes. Clone S15G10 has been shown to be useful for western blotting, immunoprecipitation, and immunoflorence staining of human SIK2 protein.

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SPECIFICATIONS

Catalog Number

636702

Size

100 microg

Applications

IF, IP, WB

Hosts

Mouse

Reactivities

Hum

Clone

S15G10

Antigen

Recombinant human SIK2

Gene Id

23235

Isotype

Mouse IgG1, kappa

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by immunofluorescence staining. For immunofluorescence microscopy: Use a dilution range of 1:100~1:400. It is recommended that the reagent be titrated.

Storage Temp

4 C

Concentration

0.5 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

Upon receipt, store undilutedat4C.\"

Alternative Names

Serine/threonine protein kinase SNF1 like kinase 2, Qin-induced kinase

Regulatory Status

RUO