Purified anti-RORalpha

Retinoid related orphan receptor alpha (ROR alpha) is a NR1 Thyroid Hormone Like Receptor. Three different subtypes ROR alpha, beta, and gamma have been discovered. ROR alpha plays a key role in the development of the cerebellum. Deletion of ROR alpha in mice causes severe impairment in the differentiation of cerebellar Purkinje neurons and results in the "staggerer" phenotype. ROR alpha has been suggested in the regulation of a number of other physiological processes, including bone formation. Recently, ROR alpha was reported to regulate lymphocyte development and mediate Th17 differentiation synergistically with ROR gamma.

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SPECIFICATIONS

Catalog Number

638802

Size

100 microl

Applications

WB

Hosts

Rabbit

Clone

Poly6388

Antigen

Synthetic peptide

Gene Id

6095

Isotype

Rabbit Polyclonal

Clonality

Polyclonal

Dilutions

Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 0.5 to 1.0 microg/ml antibody dilution for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

-20 C

Concentration

Shipping Temp

Ambient RT

Storage Buffer

Upon receipt, store frozen at -20 C.

Alternative Names

RORA

Regulatory Status

RUO