Purified anti-rat CD106

CD106 is a 110 kD transmembrane protein also known as VCAM-1 and INCAM-110. It is an immunoglobulin superfamily member and is expressed on bone marrow stromal cells, myeloid cells, splenic dendritic cells and endothelial cells (activated by cytokines). CD106 is a counter-receptor for VLA-4 (alpha4beta1 integrin) and LPAM-1 (alpha4beta7 integrin). The interactions of CD106 and VLA-4 or LPAM-1 play an important role in binding of leukocytes to activated endothelial cells and leukocyte extravasation at inflammatory sites.

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SPECIFICATIONS

Catalog Number

200401

Size

50 microg

Applications

FC, IHC

Hosts

Mouse

Reactivities

Rat

Clone

MR106

Antigen

Rat VCAM-1 transfected L5178Y cells

Gene Id

22329

Isotype

Mouse IgG1, kappa

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?1.0 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

0.5 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C.

Alternative Names

VCAM-1, INCAM-110

Regulatory Status

RUO