Purified anti-PKC

PKC, also known as protein kinase C, belongs to a kinase family involved in intracellular signaling processes. PKC isoforms are divided into three groups known as conventional (including PKCalpha, PKCbeta1, PKCbeta2 and PKCgamma), novel (including PKCepsilon, mu, theta, delta, eta), and atypical PKC isoforms (such as xi). Conventional PKC isoforms require calcium and diacylglycerol for activation, novel isoforms require diacylglycerol, and atypical isoforms require neither calcium nor diacylglycerol. Once activated by phosphorylation, the PKCs phosphorylate a large variety of substrates involved in cell differentiation, proliferation, and activation. The PKC0103 antibody recognizes human, mouse, and rat PKC and is useful for Western blotting and immunoprecipitation.