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Purified anti-NF-kappaB p65

Purified anti-NF-kappaB p65

Cat no: 653002

Supplier: BioLegend
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NF-kB p65 is a member of REL-like domain containing protein family, which forms NF-kB complex with the other family members: NF-kappaB1 (p105/p50) or NF-kappaB2 (p100/p52). The NF-kB complex is inactivated and held in the cytoplasm by the NF-kB inhibitor IkB. In response to activation stimuli, IkB kinases (IKKs) phosphorylate IkB, resulting in degradation of IkB and liberation of NF-kB complex. The activated NF-kB complex translocates to the nucleus and binds to kB sites in the DNA of their target genes.
Catalogue number: 653002
Reactivities: Human, Mouse, Rat
Hosts: Mouse
Applications: Western Blot
Size: 100 microg
Clone: 14G10A21
Gene: 4790
Dilutions: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.1-0.5 microg per ml. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: Upon receipt, store undiluted at 4C.
Concentration: 0.5 mg/ml
Antigen: Partial human NF-kappaB p65 recombinant protein (451-551 aa)
Isotype: Mouse IgG2b, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: Nuclear factor NF-kappa-B p65 subunit (NF-kB p65), Rel-A, transcription factor p65, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (NFKB3)
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