Purified anti-NF-kappaB p65

NF-kB p65 is a member of REL-like domain containing protein family, which forms NF-kB complex with the other family members: NF-kappaB1 (p105/p50) or NF-kappaB2 (p100/p52). The NF-kB complex is inactivated and held in the cytoplasm by the NF-kB inhibitor IkB. In response to activation stimuli, IkB kinases (IKKs) phosphorylate IkB, resulting in degradation of IkB and liberation of NF-kB complex. The activated NF-kB complex translocates to the nucleus and binds to kB sites in the DNA of their target genes.

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SPECIFICATIONS

Catalog Number

653002

Size

100 microg

Applications

WB

Hosts

Mouse

Reactivities

Hum, Mouse, Rat

Clone

14G10A21

Antigen

Partial human NF-kappaB p65 recombinant protein (451-551 aa)

Gene Id

4790

Isotype

Mouse IgG2b, kappa

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.1-0.5 microg per ml. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

0.5 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

Upon receipt, store undiluted at 4C.

Alternative Names

Nuclear factor NF-kappa-B p65 subunit (NF-kB p65), Rel-A, transcription factor p65, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (NFKB3)

Regulatory Status

RUO