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Purified anti-mTOR Phospho (Ser2481)

Purified anti-mTOR Phospho (Ser2481)

Cat no: 651702

Supplier: BioLegend
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mTOR (mammalian target of rapamycin) is a Ser/Thr kinase acting as an ATP sensor and is reported to autophosphorylate Ser2481 in the presence of sufficient nutrients. Activated mTOR phosphorylates ribosomal protein S6 kinase 1 (S6K1) and the eukaryotic translation initiation factor 4E binding protein 1 (4EBP1) in response to PI3K/Akt signaling, in turn, promoting cell growth, survival, and proliferation.
Catalogue number: 651702
Reactivities: Human
Hosts: Rabbit
Applications: Western Blot
Size: 200 microl
Clone: Poly6517
Gene: 2475
Dilutions: Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 microl antibody per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: Upon receipt, store undiluted at -20C.
Antigen: Modified synthetic peptide
Isotype: Rabbit Ig
Clonality: Polyclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: -20 C
Alternative names: Mammalian target of rapamycin (mTOR), RAPT1, FK506 binding protein 12-rapamycin associated protein 1 (FRAP1)
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