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Purified anti-mouse VEGFR-3 (FLT-4)
BioLegend

Supplier:

BioLegend

Cat no: 140902

Purified anti-mouse VEGFR-3 (FLT-4)

VEGFR-3, also known as FLT4, is a member of the Tyr protein kinase family. The extracellular portion of VEGFR-3 contains 7 immunoglobulin (Ig)-like domains and the cytoplasmic portion contains a protein kinase domain. FLT4 regulates angiogenesis and lymphangiogenesis, its ligands are VEGF-C and D and its binding is mediated by the 2nd and 3rd Ig-like domains of FLT4. During fetal development VEGFR-3 is expressed on endothelial cells, however, in the adult mice, the vascular endothelial cells lose VEGFR-3 expression, but the lymphatic endothelium expresses it constitutively. In addition, VEGFR-3 expression can be induced in tumors with active angiogenesis.

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SPECIFICATIONS

Catalog Number

140902

Size

500 microg

Applications

ELISA, IHC, IP, WB

Hosts

Rat

Reactivities

Mouse

Clone

AFL4

Antigen

VEGFR-3-Fc fusion protein

Gene Id

14257

Isotype

Rat IgG2a, kappa

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by immunohistochemical staining of mouse frozen tissue sections.

Storage Temp

4 C

Concentration

0.5 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C.

Alternative Names

Vascular endothelial growth factor receptor 3, FLT-4, Fms-like tyrosine kinase 4

Regulatory Status

RUO

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

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