Purified anti-mouse IDO

The mIDO-48 monoclonal antibody recognizes mouse IDO also known as Indolamine 2,3-dioxygenase, Indole 2,3-dioxygenase, and Indoleamine-pyrrole 2,3-dioxygenase. This antibody does not appear to react with human IDO. IDO is a ubiquitously expressed cytoplasm protein with a predicted molecular weight approximately 45 kD. Indoleamine 2,3-dioxygenase (IDO) is one the best known IFN-gamma inducible genes. The product of IDO gene catalyzes the degradation of the essential amino acid L-tryptophan to N-formylkynurenine. IDO has been implicated in protection against intracellular and extracellular pathogens. It also has been shown to maintain the special immune suppressive status of immune-privileged sites such as the brain, eyes, kidney, and placenta. The IDO antibody has been shown to be useful for western blotting and Immunohistochemistry.

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SPECIFICATIONS

Catalog Number

122402

Size

100 microg

Applications

IHC, WB

Hosts

Rat

Reactivities

Mouse

Clone

mIDO-48

Antigen

Recombinant mouse IDO protein

Gene Id

15930

Isotype

Rat IgG2b, kappa

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10-20 microg per 5 ml antibody dilution buffer for each mini-gel. For immunohistochemical staining of frozen sections, the suggested use of this reagent is 4 to 10 microg/ml. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

0.5 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C.

Alternative Names

Indolamine 2,3-dioxygenase, Indole 2,3-dioxygenase, Indoleamine-pyrrole 2,3-dioxygenase

Regulatory Status

RUO