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Purified anti-mouse/human CD258 (LIGHT)

Purified anti-mouse/human CD258 (LIGHT)

Cat no: 137102

Supplier: BioLegend
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CD258, also known as LIGHT, belongs to the tumor necrosis factor (TNF) superfamily. CD258 is a homotrimer composed of type II single-pass chains. The cleavage of this molecule from the cell surface results in a soluble form of LIGHT. CD258 stimulates T cell proliferation, CTL activity, Th1 cytokine production and induces apoptosis in some tumor lines. CD258 is expressed by T cells, NK cells, macrophages and platelets. The receptors of LIGHT are HVEM, LTbetaR and DCR3. CD258 has an important role in the cell-mediated immune response and in graft versus host disease.
Catalogue number: 137102
Reactivities: Human, Mouse
Hosts: Mouse
Applications: ELISA, Immunoprecipitation
Size: 500 microg
Clone: 15B2
Gene: 50930, 8740
Dilutions: Each lot of this antibody is quality control tested by ELISA. For ELISA, the suggested use of this reagent is 10 microg/ml. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C.
Concentration: 0.5 mg/ml
Antigen: Recombinant extracellular domain of murine LIGHT
Isotype: Mouse IgG1, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: LIGHT, TNFSF14, LTgamma, HVEM-L, Ly113, TR2
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