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Purified anti-mouse CD253 (TRAIL)

Purified anti-mouse CD253 (TRAIL)

Cat no: 109302

Supplier: BioLegend
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CD253 is a 40 kD TNF superfamily member known as TRAIL, Apo-2 ligand, and Apo-2L. TRAIL is expressed on a variety of cells, including IL-2 and IL-15 activated NK cells and activated T cells. However, it is undetectable on resting T and B cells. TRAIL has been reported to induce apoptosis in tumor and transformed cell lines by a caspase-dependent process. The N2B2 antibody has been reported to be useful for flow cytometric staining and blocking NK cell cytotoxicity in vitro.
Catalogue number: 109302
Reactivities: Mouse
Hosts: Rat
Applications: Flow Cytometry
Size: 500 microg
Clone: N2B2
Gene: 22035
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.25 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C.
Concentration: 0.5 mg/ml
Antigen: Mouse TRAIL-transfected 2PK-3 cells
Isotype: Rat IgG2a, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: TRAIL, Apo-2 ligand, Apo-2L, TNFSF10
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