Purified anti-MCM7

The MCM7 protein (DNA replication licensing factor 7) is a member of the MCM family that forms a heterohexamer with other family members. This nuclear protein functions in the initiation of eukaryotic genome replication. MCM7 forms a complex with MCM4, and MCM6 (two subunits of MCM7, two subunits of MCM4 and two subunits of MCM7). This complex regulates the helicase activity of the pre-replication complex and is and involved in the formation of replication forks. MCM7 is regulated ubiquitination. In addition to MCM4 and MCM6, this protein has been shown to interact with Cdk4. Two isoforms of MCM7 have been reported with molecular weights of 61 kD and 90 kD. The Poly6027 antibody recognizes the C-terminal region of both human and mouse MCM7 and has been shown to be useful for Western blotting.

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SPECIFICATIONS

Catalog Number

602702

Size

200 microl

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse

Clone

Poly6027

Antigen

Recombinant, C-terminal

Gene Id

4176

Isotype

Rabbit Polyclonal

Clonality

Polyclonal

Dilutions

Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 microl per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

-20 C

Concentration

Shipping Temp

Ambient RT

Storage Buffer

Upon receipt, store frozen at -20 C.

Alternative Names

DNA replication licensing factor MCM7

Regulatory Status

RUO