Purified anti-MCM4

The MCM4 protein (minichromosome maintenance protein 4) is a nuclear 100 kD DNA-dependent ATPase. The MCM4 protein is a component of the DNA pre-replication complex that acts to allow DNA to undergo single round of replication per cell cycle. MCM4 together with MCM6 and MCM7 have DNA helicase activity. MCM4 can be modified by phosphorylation by CDK2. Phosphorylation of MCM4 inhibits DNA replication. MCM4 has been reported to interact with the MCM6 and MCM7 (to form a 600 kD complex with helicase activity) and CDK2. The Poly6024 antibody recognizes human MCM4 and has been shown to be useful for Western blotting.

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SPECIFICATIONS

Catalog Number

602402

Size

200 microl

Applications

IP, WB

Hosts

Rabbit

Reactivities

Hum

Clone

Poly6024

Antigen

Peptide

Gene Id

4173

Isotype

Rabbit Polyclonal

Clonality

Polyclonal

Dilutions

Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 microl per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

-20 C

Concentration

Shipping Temp

Ambient RT

Storage Buffer

Upon receipt, store frozen at -20 C.

Alternative Names

Minichromosome maintenance protein 4

Regulatory Status

RUO