Home  >  Products  >  Purified anti-Mcl-1
Purified anti-Mcl-1

Purified anti-Mcl-1

Cat no: 613602

Supplier: BioLegend
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Mcl-1 (myeloid cell leukemia-1) is a 37 kD Bcl-2 related protein found in mitochondrial and non-mitochondrial membranes that dimerizes with Bax. Mcl-1 has been shown to act as a survival factor for hematopoietic cells and contribute to the STAT-dependent protection of neutrophils against apoptosis. Mcl-1 is increased by PMA, GM-CSF, M-CSF, IL-1beta, IL-3, and IL-6 in hematopoietic cells. This protein is decreased following growth factor withdrawal. Mcl-1 is modified by JNK phosphorylation. The Poly6136 antibody has been shown to recognize mouse Mcl-1 and has been shown to be useful for Western blotting.
Catalogue number: 613602
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: Western Blot
Size: 200 microl
Clone: Poly6136
Gene: 4170
Dilutions: Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 microl per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: Upon receipt, store frozen at -20 C.
Antigen: Recombinant (partial)
Isotype: Rabbit Polyclonal
Clonality: Polyclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: -20 C
Alternative names: Myeloid cell leukemia-1
See Full Product Listings >