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Purified anti-LEF1

Purified anti-LEF1

Cat no: 653101

Supplier: BioLegend
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Lymphoid Enhancing Factor 1 (LEF1) is a transcription factor belonging to the TCF/LEF family. LEF1 was first identified as a protein binding to TCR-alpha enhancer and upregulates expression of T-cell antigen receptor alpha chain. LEF1 is involved in Wnt signaling pathways as a ubiquitous regulator. During Wnt signaling, translocation of beta-catenin from the cytosol to the nucleus results in elevation of transcriptional activity of LEF1, which subsequently regulates multiple downstream genes.
Catalogue number: 653101
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunocytochemistry, Western Blot
Size: 25 microg
Clone: 15H5A18
Gene: 51176
Dilutions: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.1-0.5 microg per ml. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: Upon receipt, store undiluted at 4C.
Concentration: 0.5 mg/ml
Antigen: Partial human LEF1 recombinant protein (1-298 aa)
Isotype: Mouse IgG1, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: Lymphoid enhancer-binding factor 1, T cell-specific transcription factor 1-alpha (TCF1-alpha), TCF10, LEF-1, TCF1ALPHA, TCF7L3
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