Purified anti-IDO2

Indoleamine 2,3-dioxygenase 2 (IDO2) is related to IDO1/IDO, and may play a role in T and B cell immunity. IDO2 is not as widely expressed as IDO, but like its relative, it is also expressed in antigen-presenting dendritic cells where tryptophan catabolism drives immune tolerance. Like IDO, IDO2 catabolizes tryptophan, triggers phosphorylation of the translation initiation factor eIF2alpha, and mobilizes translation of LIP, an inhibitory isoform of the immune regulatory transcription factor NF-IL6 (nuclear factor for interleukin-6).

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SPECIFICATIONS

Catalog Number

654402

Size

500 microl

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse

Clone

Poly26544

Antigen

Complete protein containing a mixture of human and mouse IDO2 H6-tagged protein.

Gene Id

169355, 209176

Isotype

Rabbit Polyclonal IgG

Clonality

Polyclonal

Dilutions

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, use 20microl - 25 microl per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

Shipping Temp

Ambient RT

Storage Buffer

Upon receipt, store undiluted at 4C.

Alternative Names

Indoleamine 2,3-dioxygenase 2, INDOL1, Indoleamine 2,3-dioxygenase-like protein 1

Regulatory Status

RUO