Purified anti-Human Podoplanin

Podoplanin is a 40-43 kD type-I transmembrane sialomucin-type glycoprotein, also known as T1a, gp36, gp38, gp40, or Aggrus. Originally detected on the surface of podocytes, futher characterization showed podoplanin has a broad tissue distribution including many mesothelial cells, epithelial cells, follicular dendritic cells and a variety of tumor cells. It has been reported that podoplanin is the ligand of CLEC-2 and is involved in lymphatic vessel formation, platelet aggregation, and tumor metastasis. Podoplanin may serve as a useful marker for tumor diagnosis and prognosis.

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SPECIFICATIONS

Catalog Number

337002

Size

100 microg

Applications

FC, IF, IHC, IP, WB

Hosts

Rat

Reactivities

Hum

Clone

NC-08

Gene Id

10630

Isotype

Rat IgG2a, lambda

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, it is recommended to use at 1.0 microg per 106 cells in 100 microl volume or 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

0.5 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C.

Alternative Names

T1a, gp38, stromal cell marker

Regulatory Status

RUO