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Purified anti-human LT-alpha (TNF-beta)

Purified anti-human LT-alpha (TNF-beta)

Cat no: 503102

Supplier: BioLegend
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Lymphotoxin-alpha (LT-alpha), also known as tumor necrosis factor-beta (TNF-beta), is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells. LT-alpha possesses a signal peptide sequence and is a secreted protein; however, LT-alpha is also present on the surface of activated T, B and LAK cells as a complex with LT-beta. Bioactive LT-alpha exists as a homotrimer.
Catalogue number: 503102
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry
Size: 500 microg
Clone: 359-81-11
Gene: 4049
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 0.5 microg per 106 cells in 100 microl volume. The purified 359-81-11 has been tested by blocking fluorochrome conjugated 359-81-11 for intracellular cytokine staining. In order to obtain complete blocking results, a saturated amount of purified antibody (? 5.0 ug/million cells) should be used for incubation with target cells, prior to staining with fluorochrome conjugated antibody. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C.
Concentration: 0.5 mg/ml
Antigen: E. coli expressed, recombinant human LT-alpha.
Isotype: Mouse IgG1, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: Tumor necrosis factor-beta, Lymphotoxin-alpha (LT- alpha), Coley
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