Purified anti-human LT-alpha (TNF-beta)

Lymphotoxin-alpha (LT-alpha), also known as tumor necrosis factor-beta (TNF-beta), is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells. LT-alpha possesses a signal peptide sequence and is a secreted protein; however, LT-alpha is also present on the surface of activated T, B and LAK cells as a complex with LT-beta. Bioactive LT-alpha exists as a homotrimer.

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SPECIFICATIONS

Catalog Number

503002

Size

500 microg

Hosts

Mouse

Reactivities

Hum

Clone

359-238-8

Antigen

E.coli expressed, recombinant human LT-alpha.

Gene Id

4049

Isotype

Mouse IgG1, kappa

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by ELISA assay. For ELISA capture applications, a concentration range of 1-4 microg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

0.5 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C.

Alternative Names

Tumor necrosis factor-beta, Lymphotoxin-alpha (LT- alpha), Coley

Regulatory Status

RUO