Purified anti-human GPR19

GPR19 is a 415 amino acid protein with two potential glycosylation sites and one disulfide bond that belongs to Orphan G-protein-coupled receptors (GPCRs) with unknown ligand. In mice, GPR19 is highly expressed in the nervous system during embryonic development as well as in specific regions of the mouse adult brain, including the olfactory bulb, the hippocampus, the hypothalamic nuclei, and the cerebellum. It shows low levels of expression in the heart, liver, and kidney. In humans, GPR19 has been reported in regions overlapping with the dopamine D2 receptor in the brain and peripheral nervous system. It was also found in human embryonic stem cells. GPR19 gene was reported to be overexpressed with small cell lung cancer and metastatic melanomas.

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SPECIFICATIONS

Catalog Number

357001

Size

25 microg

Applications

FC

Hosts

Mouse

Reactivities

Hum

Clone

K152D10

Antigen

N-terminal Peptide

Gene Id

2842

Isotype

Mouse IgG1, kappa

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?1.0 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

0.5 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C.

Alternative Names

G protein-coupled receptor 19, GPR-NGA

Regulatory Status

RUO