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Purified anti-human CD275 (B7-H2, ICOSL)

Purified anti-human CD275 (B7-H2, ICOSL)

Cat no: 309402


Supplier: BioLegend
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B7-H2, a member of the B7 family and the immunoglobulin superfamily, is a 40 kD protein also known as B7RP-1, B7h, B7-H2, GL50 and ICOS Ligand. Human B7-H2 is expressed by activated monocytes/macrophages and dendritic cells. B7-H2 binds to a CD28-like receptor, inducible costimulator molecule (ICOS, AILIM, CRP-1), which is expressed by activated T cells. The interaction of ICOS with B7-H2 plays an important role in the T cell costimulation pathway.
Catalogue number: 309402
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Flow Cytometry, Immunoprecipitation
Size: 100 microg
Clone: 2D3
Gene: 23308
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.5 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C.
Concentration: 0.5 mg/ml
Antigen: Human B7H2-mIg fusion protein
Isotype: Mouse IgG2b, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: B7H2, ICOS-L, B7RP-1, B7-RP1