Purified anti-human CD179b (Ig lambda5)

CD179b, also known as Ig Lambda 5, lambda5, and Ig omega, is a 22 kD, C-like protein member within the Ig superfamily. lambda5 associates with CD179a (VpreB) to form a surrogate light (SL) chain that in turn associates with the IgM heavy chain and the CD79a/CD79b heterodimer to form the pre-B cell receptor (PreBCR) complex. The function of CD179a/CD179b is still under investigation, though it has been reported that the deficiency of CD179a and/or CD179b impairs the maturation of the B cell precursors beyond the pre-B cell stage.

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SPECIFICATIONS

Catalog Number

349802

Size

100 microg

Applications

FC, ICC, IHC, IP

Hosts

Mouse

Reactivities

Hum

Clone

HSL11

Gene Id

3543

Isotype

Mouse IgG1, kappa

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?1.0 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

0.5 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C.

Alternative Names

Ig Lambda 5, lambda5, Ig omega

Regulatory Status

RUO