Purified anti-human CD179a (VpreB)

CD179a is an 18 kD Ig V-like protein expressed on pro-B and early pre-B cells. It is a member of the Ig gene superfamily, known as VpreB, VPREB1, and IGVPB. CD179a noncovalently associates with CD179b (lambda5) to form a surrogate light (SL) chain. The SL chain is complexed with membrane bound IgM heavy (microH) chain and CD79a/CD79b heterodimer to form the pre-B-cell receptor (PreBCR) complex. The function of CD179a/CD179b is still under investigation though it has been reported that the pre-BCR complex plays a critical role in B cell development.

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SPECIFICATIONS

Catalog Number

347402

Size

100 microg

Applications

FC, IP

Hosts

Mouse

Reactivities

Hum

Clone

HSL96

Gene Id

7441

Isotype

Mouse IgG1, kappa

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 1.0 microg per 106 cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

0.5 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C.

Alternative Names

M-CSFR,CSF-1R, FMS, CSF-1 Receptor

Regulatory Status

RUO