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Purified anti-human C3AR

Purified anti-human C3AR

Cat no: 345802

Supplier: BioLegend
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C3AR is a single chain protein of 482 aa, with seven membrane-spanning regions and a molecular weight of 54 Kd. C3AR is expressed by neutrophils, eosinophils, mast cells, monocytes, dendritic cells and there are reports of C3AR expression in non-immune cells such as hematopoietic and mesenchymal stem cells, epithelial and endothelial cells. C3AR is coupled to heterotrimeric G proteins and after C3a binding, the signal transduced, results in chemotaxis, granule enzyme release and superoxide anion production.
Catalogue number: 345802
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunoprecipitation
Size: 100 microg
Clone: hC3aRZ8
Gene: 719
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 0.5 microg per 106 cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C.
Concentration: 0.5 mg/ml
Antigen: hC3aR transfected cells
Isotype: Mouse IgG2b
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: C3a anaphylatoxin chemotactic receptor, C3a-R, AZ3B, HNFAG09
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