Purified anti-human C3AR

C3AR is a single chain protein of 482 aa, with seven membrane-spanning regions and a molecular weight of 54 Kd. C3AR is expressed by neutrophils, eosinophils, mast cells, monocytes, dendritic cells and there are reports of C3AR expression in non-immune cells such as hematopoietic and mesenchymal stem cells, epithelial and endothelial cells. C3AR is coupled to heterotrimeric G proteins and after C3a binding, the signal transduced, results in chemotaxis, granule enzyme release and superoxide anion production.

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SPECIFICATIONS

Catalog Number

345802

Size

100 microg

Applications

FC, IP

Hosts

Mouse

Reactivities

Hum

Clone

hC3aRZ8

Antigen

hC3aR transfected cells

Gene Id

719

Isotype

Mouse IgG2b

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 0.5 microg per 106 cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

0.5 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C.

Alternative Names

C3a anaphylatoxin chemotactic receptor, C3a-R, AZ3B, HNFAG09

Regulatory Status

RUO